This one-week course covers the relation of structure and function in the case of neural systems subserving motor control. These lectures explore the basic neuroanatomy and neurophysiology of the vertebrate motor system. Illustrations will be drawn from the human being and from animal models. Emphasis will be put on the properties of several key systems, among them the spinal cord, motor cortex, cerebellum/vestibular system and basal ganglia. Further topics include normal and pathological functioning and neural coding. Lectures will be supplemented with reading and discussion of selected original research reports.